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The microbial balance of our gut directly influences our Hypothalamic-Pituitary-Adrenal (HPA) axis, the production of hormones and neurotransmitters, and our immune system's regulation. Stress is very debilitating and causes depletion of magnesium because of excessive magnesium loss via the kidneys.  Magnesium deficiency causes energy depletion and acidosis, which triggers inflammatory states, resulting in moods swings, hormone imbalance, mental illnesses, fatigue, irritability, pain symptoms, and a weaker immune system. Magnesium deficiency also directly affects the beneficial bacteria, which thus leads to depressive-like behaviours.

Magnesium is an essential mineral which performs some very important functions when you're pregnant. It’s used to maintain healthy blood sugar levels in the body (see study) and it helps build healthy teeth and bones by working in partnership with calcium. It also regulates cholesterol and irregular heartbeat.

Magnesium deficiency or antagonism (blockage) can cause any one of these steps to malfunction, causing overdose of stress hormones and inability to relax enough to sleep deeply.

It's almost impossible for you to get a toxic magnesium dose or overdose, unless magnesium is given at high dose intravenously, where there is no magnesium deficiency or the person has kidney problems and can’t excrete excess salts. 

We can become addicted to more than just pharmaceutical drugs or alcohol.  Researchers are now noticing symptoms of addiction also to excessive exercise.  Does excessive exercise or over-training have negative side effects?  Could it harm health and cause premature ageing?  The research indicates yes, mainly because of increasing magnesium deficiency.

Magnesium deficiency weakens performance, stamina and increases risk of injury When you push your muscles hard your brain is telling your body to ‘squeeze’ and act. Adrenalin and cortisol increase, and that helps push the calcium into the calcium channels of the muscle fibre cells, which makes them contract. Magnesium is temporarily pushed out of these channels during the contractions. When we relax, calcium comes out and magnesium moves back into the channels to relax the muscles again. 

I was over 50 when menopause set in, accompanied by an autoimmune disorder called Hashimotos Hypothyroidism, severe heart arrhythmia, and the emerging white patches on my skin. This form of autoimmune hypothyroidism is thought to be prevalent in about 5% of the world’s population, however I believe the numbers are growing as people become more chemically sensitive to pollutants that stress the thyroid.

The haemoglobin of red blood cells requires magnesium to help it take up oxygen from lungs and deliver that oxygen to tissue cells in other parts of the body. Researchers believe this is because, as part of the ATP energy currency, magnesium is vital to membrane integrity of red blood cells. The heme protein (containing iron) in these cells needs to ‘attract’ oxygen molecules from lung sacs as blood passes by. The oxygen molecules need to pass through the red blood cell (RBC) membrane – to get ‘onboard’ the train so to speak.

Note that dehydrated states can cause feelings of anxiety where we just don’t know the reason for our fear or agitation, but the feeling persists.  Re-hydrating the body with ample water and magnesium can calm down these sensations because magnesium has a dampening effect on adrenaline and cortisol.  When the brain has ample water and magnesium we can think more clearly and make better decisions.  This is especially important during crises because our magnesium reserves can become dangerously low.

Magnesium is so important to cardiovascular function, its scarcity being correlated with the development of cardiovascular disease, that it has become the focus of intense scientific study and review over recent years.  A meta-analysis review of epidemiological studies published in 2017 concluded that magnesium intake is associated with lower risk of major cardiovascular risk factors such as metabolic syndrome, diabetes and hypertension, as well as incidence of stroke and total cardiovascular disease.  Higher levels of circulating magnesium are also associated with lower risk of heart disease, mainly ischemic and coronary heart disease.

You may not realise it, but cramps and restless legs are quite easy to fix and you can do it without drugs.  All you need is enough magnesium (and water) to get to where it is needed in the muscles for recovery and performance.

As magnesium drops lower from excessive stress, there is less control over adrenaline and cortisol release, so that these catecholamines (stress hormones) escalate and chronically flood the system in a fight or flight (sympathetic) mode.  We can get stuck in that mode, unable to relax and move back to rest and recover grazing (parasympathetic) mode.  The stress hormones prompt glutamine to overstimulate neurons causing rapid and incessant calcium firing.  Without enough magnesium to control the calcium and switch off the catecholamine release, we can’t relax.

It’s been coined the master mineral and deemed as critical as water. But how exactly does it correlate to the process of ageing? The ways are numerous, but we’ll highlight a few of our standouts. From menopause to migraines, bone health to beautiful skin, you’ll be eager to lather up in magnesium cream by the time you’ve finished reading this. And remember, even if you’ve had a blood test that did not show up a deficiency in magnesium, only a small portion of magnesium stores actually sit in the blood. There are other areas more likely to be depleted that won’t be detected so simply.

Optimal nutrition for our children means they will have the best opportunity to realise their fullest genetic potential to be well balanced, healthy and happy into adulthood.  We all want our children to be ‘upgrades’ from ourselves. We want to pass on our seeds to future generations, but what about the quality of those seeds when magnesium is low? Can ‘magnesium kids’ offer a better hope for optimal health over a lifetime?

Healthy cells need lipid protection, magnesium charge and ample hydration to support mitochondrial energy metabolism of Mg-ATP ‘batteries’.  This energy is then used to assemble amino acids into the various proteins we need to build collagen structures.  It is also used to manufacture hormones, enzymes, neurotransmitters and other chemical messengers.

The review goes on to explain glyphosate’s mechanism of toxic action. Firstly, it is a strong chelating agent, creating complexes that immobilize the mineral micronutrients of the soil, such as magnesium, calcium, iron, manganese, nickel and zinc, making them unavailable to plants. This means that the food supply is robbed of vital mineral nutrients. We eat the food, it fills a void, but it doesn’t supply valuable nutrition. The end result is that we keep eating more and more empty carbs until obesity and other metabolic diseases such as hypertension, diabetes, senile dementia, inflammatory bowel disease, renal failure, thyroid or liver cancer develop.